Ancient DNA reveals the deadly diseases behind Napoleon’s defeat

Science DailyCenterEN 3 min read 100% complete October 26, 2025 at 09:36 AM
Ancient DNA reveals the deadly diseases behind Napoleon’s defeat

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medium article 3 min

Scientists from the Institut Pasteur have discovered traces of pathogens causing paratyphoid fever and relapsing fever in the remains of French soldiers who retreated from Russia in 1812. The findings were initially shared as a preprint on bioRxiv on July 16, 2025, and later published in Current Biology on October 24. Researchers analyzed DNA samples from 13 soldiers exhumed in Vilnius, Lithuania, using next-generation sequencing technology to identify the pathogens Salmonella enterica subsp. enterica (serovar Paratyphi C) and Borrelia recurrentis. This study provides direct genetic evidence of these diseases among Napoleon's troops during their retreat from Russia, contributing to a better understanding of the health challenges faced by the soldiers.

Keywords

ancient dna 90% napoleon's defeat 85% genetic analysis 80% paratyphoid fever 75% relapsing fever 75% 1812 retreat 70% next-generation sequencing 70% salmonella enterica 65% borrelia recurrentis 65% institut pasteur 60%

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Russia

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