People who stop taking weight-loss jabs regain weight in under two years, study reveals

The Guardian - World NewsCenter-LeftEN 3 min read 100% complete by Tobi Thomas Health and inequalities correspondentJanuary 8, 2026 at 12:30 AM
People who stop taking weight-loss jabs regain weight in under two years, study reveals

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A new study led by the University of Oxford and published in the BMJ reveals that individuals who discontinue weight loss medications, specifically GLP-1 agonists, regain lost weight rapidly. The research, a review of 37 studies involving over 9,000 participants, found that on average, people regained weight at a rate of 0.4kg per month after stopping medication, returning to their original weight within approximately 1.7 years. This weight regain occurred almost four times faster than after stopping behavioral weight loss programs. Researchers emphasize that this rapid regain highlights the chronic nature of obesity and the need for comprehensive, long-term weight management strategies beyond short-term medication use, as the benefits to cardio-metabolic health also diminished.

Keywords

weight loss 100% weight regain 90% weight loss medication 80% glp-1 agonists 80% obesity treatment 60% behavioural programmes 60% chronic condition 50% diabetes 40%

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Center-Left (-0.40)
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90%

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