People who stop taking weight-loss jabs regain weight in under two years, study reveals

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A new study led by the University of Oxford and published in the BMJ reveals that individuals who discontinue weight loss medications, specifically GLP-1 agonists, regain lost weight rapidly. The research, a review of 37 studies involving over 9,000 participants, found that on average, people regained weight at a rate of 0.4kg per month after stopping medication, returning to their original weight within approximately 1.7 years. This weight regain occurred almost four times faster than after stopping behavioral weight loss programs. Researchers emphasize that this rapid regain highlights the chronic nature of obesity and the need for comprehensive, long-term weight management strategies beyond short-term medication use, as the benefits to cardio-metabolic health also diminished.
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