China’s 7,000-year-old sunmao woodwork leads to world’s most efficient DNA editing tool

South China Morning PostCenter-RightEN 1 min read 100% complete by Shi HuangJanuary 16, 2026 at 09:48 AM
China’s 7,000-year-old sunmao woodwork leads to world’s most efficient DNA editing tool

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A research team from Peking University and the Chinese Academy of Sciences developed a highly efficient DNA editing tool inspired by the ancient Chinese sunmao woodwork technique. The sunmao, a mortise-and-tenon joint dating back 7,000 years to China's Hemudu culture, uses interlocking pieces without nails or glue. Applying this concept to gene editing, the team created a tool that achieves insertion and replacement efficiencies up to 59.47% in rice. At certain genomic loci, the new tool's editing efficiency is reportedly ten times higher than traditional Cas9-based systems. The tool represents a significant advancement in gene editing technology.

Keywords

gene editing 100% sunmao woodwork 90% dna editing tool 80% mortise-and-tenon joint 70% editing efficiency 60% peking university 50% chinese academy of sciences 50% cas9-based systems 40% genomic loci 40%

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South China Morning Post
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Center-Right (0.50)
Far LeftCenterFar Right
Classification Confidence
90%
Geographic Perspective
China

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