Grey's Anatomy star Eric Dane dies at 53 after ALS diagnosis

BBC News - WorldEN 2 min read 100% complete February 20, 2026 at 07:01 AM

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Actor Eric Dane, best known for his roles in *Grey's Anatomy* and *Euphoria*, has died at age 53 following a battle with amyotrophic lateral sclerosis (ALS). Dane revealed his diagnosis in April 2025 and spent his final months raising awareness for the disease. He gained fame as Dr. Mark Sloan on *Grey's Anatomy* and later played Cal Jacobs in *Euphoria*. Dane also appeared in *Charmed*, *The Last Ship*, and films like *Marley & Me* and *Valentine's Day*. He is survived by his wife, Rebecca Gayheart, and their two daughters. Tributes are being made by Dane's *Grey's Anatomy* co-stars.

Key Entities & Roles

Key Player Opposition Context

San Francisco 30% Kevin McKidd 30% Kim Raver 30% California 35% HBO 40% Rebecca Gayheart 50% Euphoria 60% Grey's Anatomy ×470% ALS (Amyotrophic Lateral Sclerosis) ×485% Eric Dane ×795%

Keywords

eric dane 100% als 100% death 90% grey's anatomy 80% amyotrophic lateral sclerosis 70% actor 70% euphoria 60% motor neurone disease 50% medical drama 40%