FDA to weigh easing limits on unproven peptides favored by RFK Jr. and other MAHA figures

Secretary of Health and Human Services Robert F. Kennedy, Jr. speaks during a fireside chat with CPAC Senior Fellow Mercedes Schlapp at the Conservative Political Action Conference (CPAC) in Dallas, Saturday, March 28, 2026. (AP Photo/Gabriela Passos) 2026-04-15T13:15:23Z WASHINGTON (AP) — The Food and Drug Administration will hold a meeting this summer to consider easing restrictions on more than a half dozen peptide injections , a group of unapproved therapies that have become popular among wellness influencers, fitness gurus and celebrities . The meeting announcement Wednesday follows repeated pledges by Health Secretary Robert F. Kennedy Jr. to loosen regulations on peptides, which are often pitched as a quick way to build muscle, heal injuries or appear younger. There’s little research behind those claims and most peptides have not been reviewed for safety by the FDA. Kennedy has discussed using peptides for his own injuries. And some major supporters of his Make America Healthy Again movement are big proponents of them, including Gary Brecka, a self-described “longevity expert” who sells various peptide formulas through his website. freestar.queue.push(function () { window.fsAdCount = window.fsAdCount + 1 || 0; let customChannel = '/dynamic_' + fsAdCount; let adList = document.querySelectorAll(".fs-feed-ad") let thisAd = adList[fsAdCount]; let randId = Math.random().toString(36).slice(2); thisAd.id = randId; let thisPlacement = fsAdCount == 0 ? "apnews_story_feed" : "apnews_story_feed_dynamic"; freestar.newAdSlots({ placementName: thisPlacement, slotId: randId }, customChannel); }); The FDA said in a federal notice Wednesday it will ask a panel of outside advisers to review seven peptides at a meeting in July, specifically whether they should be removed from a restrictive category reserved for risky, customized drugs. The peptides under discussion will include some of the most popular among influencers, such as BPC-157, which is marketed to heal injuries and reduce inflammation. “The Wild West is about to become wilder,” said Dr. Peter Lurie, a former FDA official who now leads the Center for Science in the Public Interest. In an interview, Lurie said allowing peptides on the market without clinical testing poses a “profound threat” to FDA’s decades-old system for vetting drugs. /* Desktop-first: fully collapse by default */ #ap-readmore-embed { display: none; margin: 0; padding: 0; height: 0; min-height: 0; overflow: hidden; text-align: center; position: relative; z-index: 2; } /* Only show on mobile */ @media (max-width: 767px) { #ap-readmore-embed { display: block; margin: 28px 0; height: auto; overflow: visible; } } #ap-readmore-embed .ap-readmore-btn { appearance: none; -webkit-appearance: none; border: 0; background: #000; color: #fff; cursor: pointer; display: inline-flex; align-items: center; justify-content: center; gap: 10px; padding: 14px 22px; border-radius: 999px; font-family: inherit, "AP Sans", -apple-system, BlinkMacSystemFont, "Helvetica Neue", Arial, sans-serif; font-weight: 700; font-size: 16px; letter-spacing: 0.2px; line-height: 1; box-shadow: 0 10px 18px rgba(0,0,0,0.12); transition: transform 120ms ease, box-shadow 120ms ease, opacity 120ms ease; 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var root = rootCandidates.find(function (c) { return c.contains(stopEl); }) || document.body; var all = root.getElementsByTagName("*"); var hidden = []; for (var i = 0; i “I don’t see why one would take the path of a proper drug approval if there is now this less rigorous, alternative path to market,” he said. Under President Joe Biden, the FDA added nearly 20 of the most popular peptides to the federal list of substances that should not be produced by compounding pharmacies — businesses that mix medications that aren’t available from drugmakers. freestar.queue.push(function () { window.fsAdCount = window.fsAdCount + 1 || 0; let customChannel = '/dynamic_' + fsAdCount; let adList = document.querySelectorAll(".fs-feed-ad") let thisAd = adList[fsAdCount]; let randId = Math.random().toString(36).slice(2); thisAd.id = randId; let thisPlacement = fsAdCount == 0 ? "apnews_story_feed" : "apnews_story_feed_dynamic"; freestar.newAdSlots({ placementName: thisPlacement, slotId: randId }, customChannel); }); At the time, the FDA’s panel of pharmacy advisers voted overwhelmingly that the peptides did not meet the criteria for a list of drugs that can be safely compounded. And FDA regulators agreed, saying later that the substances “present significant safety risks,” because most have not been extensively tested in humans. Many of the FDA advisers and internal staff who oversaw those decisions no longer work for the agency. The FDA’s pharmacy panel currently has a number of vacancies, which Kennedy could fill before the July meeting. At the FDA meeting in July, panelists will consider whether BPC-157, TB-500 and five other peptides should be permitted for routine compounding. The FDA notice cites several possible medical uses for the substances, such as using BPC-157 to treat ulcerative colitis. Kennedy previewed the move in an interview with podcast host Joe Rogan. Both men have repeatedly spoken about peptides and claimed to have benefited from their use. Sign up for Morning Wire: Our flagship newsletter breaks down the biggest headlines of the day. 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"apnews_story_feed" : "apnews_story_feed_dynamic"; freestar.newAdSlots({ placementName: thisPlacement, slotId: randId }, customChannel); }); Scott Brunner of the Alliance for Pharmacy Compounding said the coming meeting will be the start of a “protracted process.” Even if the panel votes to make the peptides available, and FDA agrees, the agency will still have to draft and publish rules on the change, he noted. Peptides are essentially the building blocks of more complex proteins. Inside the human body, peptides trigger hormones needed for growth, metabolism and healing. In recent years peptides have become widely known through the blockbuster success of GLP-1 medications, which the FDA has approved for treating obesity and diabetes. Other FDA-approved peptides include insulin for diabetics and hormone-based drugs for several medical conditions. freestar.queue.push(function () { window.fsAdCount = window.fsAdCount + 1 || 0; let customChannel = '/dynamic_' + fsAdCount; let adList = document.querySelectorAll(".fs-feed-ad") let thisAd = adList[fsAdCount]; let randId = Math.random().toString(36).slice(2); thisAd.id = randId; let thisPlacement = fsAdCount == 0 ? "apnews_story_feed" : "apnews_story_feed_dynamic"; freestar.newAdSlots({ placementName: thisPlacement, slotId: randId }, customChannel); }); But many of the peptides promoted online have never been approved, making them technically illegal to market as drugs. Several peptides, such as BPC-157 and TB-500, are banned by international sports authorities as doping substances . But that has not stopped them from gaining a foothold in the burgeoning marketplace for new wellness hacks and alternative remedies . In a related move, some dietary supplement makers have begun mixing peptides into capsules, protein powders and gummies. At a recent FDA meeting, the industry argued for expanding the federal definition of supplements to permit the use of newer ingredients like peptides in their products. freestar.queue.push(function () { window.fsAdCount = window.fsAdCount + 1 || 0; let customChannel = '/dynamic_' + fsAdCount; let adList = document.querySelectorAll(".fs-feed-ad") let thisAd = adList[fsAdCount]; let randId = Math.random().toString(36).slice(2); thisAd.id = randId; let thisPlacement = fsAdCount == 0 ? "apnews_story_feed" : "apnews_story_feed_dynamic"; freestar.newAdSlots({ placementName: thisPlacement, slotId: randId }, customChannel); }); Safety risks were cited previously When the FDA added a number of injectable peptides to its list of restricted substances in 2023, it cited safety risks including cancer and liver, kidney and heart problems. That triggered pushback from wellness entrepreneurs, compounding pharmacies and their allies in Washington. Last year several members of Congress, including Republican Sen. Tommy Tuberville of Alabama, sent letters to Kennedy asking him to lift limits on peptide production. The compounding industry has argued for years that FDA’s restrictions have given rise to an illicit market of imported chemicals from China and other countries, which are not subject to U.S. drug standards. Kennedy has echoed those concerns. “With the gray market you have no idea if you’re getting a good product,” Kennedy told Rogan. “And a lot of this stuff that we’ve looked at is just very, very substandard.” ___ The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education and the Robert Wood Johnson Foundation. The AP is solely responsible for all content. MATTHEW PERRONE Perrone covers the intersection of medicine, business and health policy. He is based in Washington. twitter mailto 获取更多RSS： https://feedx.net https://feedx.site