How South African scientists identified
hantavirus on a cruise ship thousands of miles away 1 of 3 | People in protective gear remove waste from the
MV Hondius cruise ship after its arrival at the
Port of Rotterdam,
Netherlands, Monday, May 18, 2026. (AP Photo/Patrick Post) 2 of 3 | The
MV Hondius cruise ship arrives at the
Port of Rotterdam,
Netherlands, Monday, May 18, 2026. (AP Photo/Patrick Post) 3 of 3 | Signs at the headquarters of
South Africa’s
National Institute for Communicable Diseases, in
Johannesburg,
South Africa, Wednesday, May 6, 2026. (AP Photo/Themba Hadebe) 1 of 3 | People in protective gear remove waste from the
MV Hondius cruise ship after its arrival at the
Port of Rotterdam,
Netherlands, Monday, May 18, 2026. (AP Photo/Patrick Post) 1 of 3 People in protective gear remove waste from the
MV Hondius cruise ship after its arrival at the
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MV Hondius cruise ship arrives at the
Port of Rotterdam,
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MV Hondius cruise ship arrives at the
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South Africa, Wednesday, May 6, 2026. (AP Photo/Themba Hadebe) 3 of 3 Signs at the headquarters of
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Johannesburg (AP) — When South African infectious disease specialist
Lucille Blumberg checked her email on the morning of May 1, while the country was celebrating the Labor Day holiday, an urgent message caught her attention.A U.K.-based colleague had written about a passenger from a cruise ship sailing thousands of miles away in the
Atlantic Ocean who had been evacuated and admitted to a
Johannesburg hospital with suspected
pneumonia. Others aboard the vessel were also sick. The colleague, who monitors diseases in remote British overseas territories in the South
Atlantic Ocean, asked Blumberg to follow up on the passenger, who had been evacuated from the ship in one of the territories, Ascension Island.Blumberg and other experts at
South Africa’s
National Institute for Communicable Diseases were suddenly thrown into the race to identify the cause of an outbreak aboard the Dutch cruise ship
MV Hondius. “Even though it was a public holiday, we moved, we moved really fast,” Blumberg told The Associated Press. “It was busy. There were many conversations. There were online discussions, and there was laboratory testing happening at the time.”Within 24 hours, they had determined that the man’s illness was caused by
hantavirus, a rare rodent-borne virus. 5 MIN READ 3 MIN READ 1 MIN READ A process of elimination to identify the diseaseThe elderly British man had arrived at a private hospital in
Johannesburg days earlier and was seriously ill, but health workers weren’t sure of the underlying cause.By the time he was evacuated from the ship, two elderly Dutch passengers who had been on board the
MV Hondius cruise liner had already died, but there had been little alarm. Ascension Island health authorities had reported a cluster of illnesses on the ship that appeared to be
pneumonia to the World Health Organization. At first, Blumberg and her colleagues thought it might be Legionella, a bacterium that causes a serious form of
pneumonia, Legionnaires’ disease. Or maybe bird flu. “I called my infectious disease colleagues, and we had a caucus, and we discussed the usual ones,” Blumberg said. “Legionella is well described in outbreaks in hotels and on cruise ships, and influenza certainly is. These people had visited islands where avian influenza is well documented.”Tests on all those were negative. The experts also ran an extensive panel of tests for other respiratory diseases. Also, all negative.The team then began looking more closely at where the ship came from — Argentina — and the fact that passengers on board were avid bird watchers and had reportedly been to parts of South America where there were birds, but also rodents. Collaboration with experts in South America and the USThat pushed the South African disease experts toward another theory: the rare, rodent-borne
hantavirus infection, which is found in parts of South America.“It’s a well-described, not common, but it’s a well-described virus in Chile and Argentina,” Blumberg said. She added that their work was aided by collaboration with
hantavirus experts from South America and the United States, facilitated by the WHO, the U.N. health agency.“You can get onto a Zoom (call) online and ask your questions and get advice. This is not something every day. So that was quite extraordinary,” Blumberg said.By then, it was Saturday morning. Blumberg called the head of the only laboratory in
South Africa that can test for
hantavirus.“I said, we want to do hanta, and she said, ‘yeah, I’m coming.’”The tests, carried out on the sick man’s blood samples, came back positive for
hantavirus that afternoon. The team did a second set of tests to be sure, Blumberg said. Finally, there was a ‘wow moment’Those positive tests, which also identified the Andes strain of
hantavirus, allowed the WHO to inform the cruise ship what it was dealing with and announce an outbreak on board. While
hantavirus is not easily spread from person to person, the WHO says the Andes virus can be transmitted between people.The test results also led Blumberg to rush to collect blood samples from a Dutch woman — one of the first two cruise passengers to die — who had disembarked from the ship with her husband’s body on the island of St. Helena and flown to
South Africa, where she died.A posthumous
hantavirus test on her was also positive.“It was a bit of a wow moment,” Blumberg said. “And at least once you know what you’re dealing with, it’s much easier to respond.”The British man who was the first confirmed case of
hantavirus infection from the cruise ship is improving in hospital,
South Africa’s health ministry has said. Meanwhile, the ship has arrived at the Dutch
Port of Rotterdam, where it was disinfected, and the remaining crew members disembarked.“I’ve been doing outbreaks for 25 years. That’s what we do. We do them every day,” she said. “I think the important thing was to respond immediately to a question that clearly was urgent and then to take it from there.”___AP coverage of the cruise ship
hantavirus outbreak: https://apnews.com/hub/
hantavirus Gumede is a
Johannesburg-based text news reporter for The Associated Press. She covers a wide range of news topics, including health, climate change, and politics in
South Africa.