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CODIS
OrganizationCODIS is the FBI's DNA database used for matching DNA profiles in criminal investigations.
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CODIS, or Combined DNA Index System, is the FBI's national DNA database. It contains DNA profiles collected from convicted offenders, arrestees (in some states), and crime scene evidence. Law enforcement agencies use CODIS to identify potential suspects by comparing DNA profiles from crime scenes to those stored in the database. The system facilitates linking crimes to each other and identifying repeat offenders. CODIS is newsworthy in the context of the Nancy Guthrie kidnapping case in Pima County, Arizona. A glove found near Guthrie's home, potentially matching one worn by a suspect seen in doorbell camera footage, was tested for DNA. However, the DNA profile obtained from the glove did not match any profiles currently in the CODIS database. This lack of a match highlights both the potential and limitations of CODIS in solving crimes. While a match can provide crucial leads, the absence of a match doesn't exclude individuals as suspects and underscores the ongoing need for other investigative methods.
Last updated: April 27, 2026
