Eric Dane, ‘Grey’s Anatomy’ star and ALS awareness advocate, dies at 53

Actor Eric Dane, best known for his roles in "Grey's Anatomy" and "Euphoria," has died at the age of 53 from amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. Dane had announced his diagnosis in April 2025 and subsequently became an advocate for ALS awareness. The actor's death was reported on February 19th. Dane was a prominent figure in the entertainment industry, appearing in various television series and films throughout his career. His advocacy work aimed to raise awareness and support for research into the debilitating disease.

Actor Eric Dane, best known for his role as Dr. Mark Sloan ("McSteamy") on *Grey's Anatomy*, died on Thursday at age 53 after battling amyotrophic lateral sclerosis (ALS). Dane, who also starred in *Euphoria*, was diagnosed with ALS less than a year prior to his death. ALS, also known as Lou Gehrig's disease, is a progressive disease that affects the connection between the brain and muscles. Dane's family stated that he passed away surrounded by friends and family, including his wife and two daughters. Throughout his battle with ALS, Dane became an advocate for awareness and research for the disease.

Actor Eric Dane, known for his roles in "Grey's Anatomy" and "Euphoria," has died at age 53, less than a year after revealing his diagnosis of amyotrophic lateral sclerosis (ALS), a form of motor neurone disease. Dane passed away on Thursday afternoon, surrounded by family. He had become an advocate for ALS awareness following his diagnosis and continued working, filming the upcoming season of "Euphoria" in a wheelchair. Dane is survived by his wife, Rebecca Gayheart, and their two daughters. He is remembered for his roles as Dr. Mark Sloan in "Grey's Anatomy" and Cal Jacobs in "Euphoria."