What to know about the latest US-Israeli attacks on Iran

What to know about the latest US-Israeli attacks on Iran 1 of 11 | The U.S. and Israel launched a major attack on Iran on Saturday, and U.S. President Donald Trump called on the Iranian public to “seize control of your destiny” by rising up against the Islamic leadership that has ruled the nation since 1979. The strikes opened a stunning new chapter in U.S. intervention in Iran and marked the second time in eight months that the Trump administration has used military force against the Islamic Republic. (AP video produced by Louis Brettkelly) 2 of 11 | Ayatollah Ali Khamenei, who assembled theocratic power in Iran over the decades as its supreme leader and sought to turn it into a regional powerhouse, bringing it into confrontation with Israel and the United States over its nuclear program while crushing democracy protesters at home, has died, Iranian state media confirmed early Sunday. 3 of 11 | U.S. President Donald Trump urged the Iranian people to “take over your government” in a video address posted Saturday. His comments came after the U.S. and Israel launched an attack on Iran. 4 of 11 | Smoke was seen rising in Tehran on Saturday after the U.S. and Israel said it launched an attack on Iran. The first apparent strike happened near the offices of Supreme Leader Ayatollah Ali Khamenei. 5 of 11 | Sirens ring out in Israel as country on high alert after launching strikes against Iran; AP explains 6 of 11 | Iranian television broadcast Saturday footage of the damage caused by a joint U.S.-Israeli strike on Tehran. The first strikes of the attack appeared to target the compound home to Iran’s 86-year-old Supreme Leader Ayatollah Ali Khamenei in downtown Tehran. 7 of 11 | People watch from a rooftop as a plume of smoke rises after a strike in Tehran, Iran, Sunday, March 1, 2026. (AP Photo/Vahid Salemi) 8 of 11 | Paramedics evacuate wounded people from the site of a deadly Iranian missile strike in Beit Shemesh, Israel Sunday, March 1, 2026. (AP Photo/Leo Correa) 9 of 11 | Police fire tear gas shell to disperse Shiite Muslims protesters near the U.S Consulate during a rally condemning the killing of Iranian Supreme Leader Ayatollah Ali Khamenei, in Lahore, Pakistan, Sunday, March 1, 2026. (AP Photo/K.M. Chaudary) 10 of 11 | Rescue workers and military personnel carry a body of a victim from the scene where several people were killed by an Iranian missile strike in Beit Shemesh, Israel Sunday, March 1, 2026. (AP Photo/Leo Correa) 11 of 11 | Paramilitary soldiers and police officers walk past a burning police’s armoured vehicle, which was set on fire by Shiite Muslims during a protest over the killing of Iranian Supreme Leader Ayatollah Ali Khamenei, in Karachi, Pakistan, Sunday, March 1, 2026. (AP Photo/Muhammad Farooq) 1 of 11 The U.S. and Israel launched a major attack on Iran on Saturday, and U.S. President Donald Trump called on the Iranian public to “seize control of your destiny” by rising up against the Islamic leadership that has ruled the nation since 1979. The strikes opened a stunning new chapter in U.S. intervention in Iran and marked the second time in eight months that the Trump administration has used military force against the Islamic Republic. (AP video produced by Louis Brettkelly) Add AP News on Google Add AP News as your preferred source to see more of our stories on Google. 2 of 11 Ayatollah Ali Khamenei, who assembled theocratic power in Iran over the decades as its supreme leader and sought to turn it into a regional powerhouse, bringing it into confrontation with Israel and the United States over its nuclear program while crushing democracy protesters at home, has died, Iranian state media confirmed early Sunday. Add AP News on Google Add AP News as your preferred source to see more of our stories on Google. 3 of 11 U.S. President Donald Trump urged the Iranian people to “take over your government” in a video address posted Saturday. His comments came after the U.S. and Israel launched an attack on Iran. Add AP News on Google Add AP News as your preferred source to see more of our stories on Google. 4 of 11 Smoke was seen rising in Tehran on Saturday after the U.S. and Israel said it launched an attack on Iran. The first apparent strike happened near the offices of Supreme Leader Ayatollah Ali Khamenei. Add AP News on Google Add AP News as your preferred source to see more of our stories on Google. 5 of 11 Sirens ring out in Israel as country on high alert after launching strikes against Iran; AP explains Add AP News on Google Add AP News as your preferred source to see more of our stories on Google. 6 of 11 Iranian television broadcast Saturday footage of the damage caused by a joint U.S.-Israeli strike on Tehran. The first strikes of the attack appeared to target the compound home to Iran’s 86-year-old Supreme Leader Ayatollah Ali Khamenei in downtown Tehran. Add AP News on Google Add AP News as your preferred source to see more of our stories on Google. 7 of 11 People watch from a rooftop as a plume of smoke rises after a strike in Tehran, Iran, Sunday, March 1, 2026. (AP Photo/Vahid Salemi) Add AP News on Google Add AP News as your preferred source to see more of our stories on Google. 8 of 11 Paramedics evacuate wounded people from the site of a deadly Iranian missile strike in Beit Shemesh, Israel Sunday, March 1, 2026. (AP Photo/Leo Correa) Add AP News on Google Add AP News as your preferred source to see more of our stories on Google. 9 of 11 Police fire tear gas shell to disperse Shiite Muslims protesters near the U.S Consulate during a rally condemning the killing of Iranian Supreme Leader Ayatollah Ali Khamenei, in Lahore, Pakistan, Sunday, March 1, 2026. (AP Photo/K.M. Chaudary) Add AP News on Google Add AP News as your preferred source to see more of our stories on Google. 10 of 11 Rescue workers and military personnel carry a body of a victim from the scene where several people were killed by an Iranian missile strike in Beit Shemesh, Israel Sunday, March 1, 2026. (AP Photo/Leo Correa) Add AP News on Google Add AP News as your preferred source to see more of our stories on Google. 11 of 11 Paramilitary soldiers and police officers walk past a burning police’s armoured vehicle, which was set on fire by Shiite Muslims during a protest over the killing of Iranian Supreme Leader Ayatollah Ali Khamenei, in Karachi, Pakistan, Sunday, March 1, 2026. (AP Photo/Muhammad Farooq) Add AP News on Google Add AP News as your preferred source to see more of our stories on Google. Updated [hour]:[minute] [AMPM] [timezone], [monthFull] [day], [year] The massive U.S. and Israeli attack on Iran killed Supreme Leader Ayatollah Ali Khamenei, triggered retaliatory strikes on multiple countries in the region and is reverberating around the world.Related violence expanded Sunday to a growing number of places, with a rising death toll. A major Israeli strike targeted Tehran. Iran fired drones and missiles at Israel and U.S. military installations around the Gulf, and also at the global business and tourism hub of Dubai. Several people were killed in clashes after protesters stormed the U.S. consulate in Pakistan.The joint U.S.-Israeli strikes on Iran, which started on Saturday, carried the potential for a wider war and the fallout could hit the world economy. Global reaction ranged from jubilation to condemnation. President Donald Trump urged Iranians to seize the moment and “take over.” The latest strikes came two days after the latest U.S.-Iran talks as Trump pressured Tehran for a deal to constrain its nuclear program. Iran’s provisional governing council started its work Sunday, and is expected to name a new supreme leader. Iran’s theocracy has struggled with growing dissent following nationwide protests that began over the economy but turned into anti-government ones. Supreme leader was one of the first targetsIsrael said it had worked with the U.S. for months to plan the attacks. The U.S. military said targets in Iran included Revolutionary Guard command facilities, air defense capabilities, missile and drone launch sites, and military airfields.One of the first strikes hit near the offices of the 86-year-old Khamenei, who had ruled since 1989 and held ultimate power. Iranian state television and state-run IRNA news agency reported Khamenei’s death, without details.Israel said it killed 40 top Iranian military officials, including the commander of Iran’s Revolutionary Guard and the defense minister. Iranian state media said at least 200 people have been killed.The U.S. and Israel also struck Iran last June during earlier nuclear talks, greatly weakening Iran’s air defenses, military leadership and nuclear program. The Trump administration has asserted that Iran had been rebuilding its nuclear program, which Tehran has insisted is for peaceful purposes. ‘Crossed our red line’Iran launched missiles and drones targeting Israel and strikes targeting U.S. military installations in Bahrain, Kuwait and Qatar. Three U.S. service members have been killed, according to U.S. Central Command.“You have crossed our red line and must pay the price,” Iran’s parliamentary speaker, Mohammad Bagher Qalibaf, said in a televised address Sunday. The authorities said 10 people have been killed in Israel, and loud explosions caused by missile impacts or interceptions could be heard in Tel Aviv. Air defense fire thudded over Dubai, the United Arab Emirates’ commercial capital, which has long drawn business and expatriates by billing itself as a safe haven in a volatile region. Shrapnel from Iranian attacks on the UAE capital of Abu Dhabi killed two people, state media said. Attacks also extended into Oman — Iran’s longtime interlocutor with the West. Saudi Arabia said Iran had targeted its capital and eastern region in an attack that was repelled. Bahrain said a missile attack targeted the U.S. Navy’s 5th Fleet headquarters, and three buildings were damaged in the capital, Manama, and Muharraq city.Kuwait’s civil aviation authority said a drone targeted the main international airport, injuring several employees. Explosions could be heard in Qatar. Jordan said it “dealt with” 49 drones and ballistic missiles.Iranian-backed Houthis in Yemen have vowed to resume attacks on Red Sea shipping routes and on Israel, according to two senior Houthi officials who spoke on condition of anonymity because there was no official announcement from leadership. Trump tells Iranians ‘take over your government’In announcing the “major combat operations,” Trump indicated the U.S. was striking for reasons beyond Iran’s nuclear program. On Friday, he voiced frustration over lack of progress in negotiations to stop Iran’s ability to develop nuclear weapons.He listed grievances stretching back to the beginning of the Islamic Republic following a revolution in 1979 that turned Iran from one of America’s closest allies in the Middle East into a foe. Iran’s ballistic missile program and support for armed proxies in the region were other issues.Trump on Saturday told Iranians to take cover but urged them to later rise up and topple the Islamic leadership.“When we are finished, take over your government,” Trump said. “It will be yours to take. This will be probably your only chance for generations.” US military plans to maintain pressureTrump later said “heavy and pinpoint bombing” in Iran would continue through the week or longer.The U.S. had assembled a fleet of fighter jets and warships in the region as it negotiated with Iran about a deal over its nuclear program. The fleet has added more than 10,000 U.S. troops to the region.The aircraft carrier USS Abraham Lincoln and three guided-missile destroyers arrived in January to bolster the number of warships. The world’s largest aircraft carrier, the USS Gerald R. Ford, and four accompanying destroyers were later dispatched from the Caribbean to head to the Middle East and are now in the Mediterranean.U.S. Democrats are leading efforts to limit Trump’s war powers, notably after he pledged to end with ’’forever wars″ abroad.Fighting impacts other countries, disrupts air travelThe strikes elicited mixed global reactions, including angry protests, celebrations and calls by world leaders for a return to negotiations and peace.At least nine people were killed in clashes with police and paramilitary forces Sunday after hundreds of Shiite protesters stormed the U.S. Consulate in the Pakistani port city of Karachi, authorities said.Shipping companies suspended their vessels’ traffic through the Suez Canal. The strikes could rattle global markets, particularly if Iran makes the Strait of Hormuz unsafe for commercial traffic. A fifth of worldwide traded oil passes through the strait.The fighting disrupted air travel in the region, with global repercussions. Hundreds of thousands of travelers were stranded or diverted to other airports after Israel, Qatar, Syria, Iran, Iraq, Kuwait and Bahrain closed their airspace. There was no flight activity over the United Arab Emirates, flight tracking website FlightRadar24 said.