Ebola virus: first person vaccinated in UK trial of new jab

The World Health Organization (WHO) estimates that the true number of Ebola cases in the Democratic Republic of the Congo (DRC) could be at least double the official tally of 1,963 confirmed cases, with at least 719 deaths. WHO's Executive Director of the Health Emergencies Programme, Chikwe Ihekweazu, stated that most deaths are occurring within families, not medical centers, and the outbreak's scale may be 2-4 times higher than reported. This warning comes as healthcare workers at the outbreak's epicenter in Ituri province are threatening to strike due to unpaid salaries since May 15th. These workers, who have been treating Ebola patients under difficult conditions, have already protested and temporarily blocked access routes at a treatment center. The article notes that healthcare workers themselves have accounted for a significant number of Ebola cases, including 112 transmissions and 35 deaths.

Staff at a hospital treating Ebola patients in the Democratic Republic of the Congo (DRC) have gone on strike due to not being paid for months. This walkout at Rwampara General Hospital in Ituri province, the outbreak's epicenter, occurred as authorities confirmed the virus has spread to two additional provinces in northern DRC: Haut-Uele and Tshopo. The striking workers include epidemiologists, case investigators, drivers, and gravediggers. This outbreak is the worst in Africa's history, with efforts to contain it complicated by rebel presence, misinformation, burial practices, and community distrust.

In the Democratic Republic of the Congo's Ituri region, the first patients have been enrolled in a record-breaking Ebola treatment trial just six weeks after the outbreak was declared a public health emergency. This trial, a collaboration involving scientists, aims to reduce mortality rates by testing two drugs: remdesivir and MBP134. These drugs have shown efficacy in animal models against the Bundibugyo strain of Ebola, which has caused 1,792 confirmed cases and 625 deaths as of July 9th. The trial randomly assigns patients to receive either drug, a combination, or standard supportive care. The research is crucial as there are currently no approved treatments for this strain, and frontline workers are facing challenges including lack of pay and community mistrust.

The Democratic Republic of the Congo's 17th Ebola epidemic has resulted in over 500 deaths, with at least 506 fatalities and 1,561 confirmed cases reported by the World Health Organization as of July 4. This outbreak is caused by the Bundibugyo virus, for which there are no existing vaccines or approved treatments. Health workers are reportedly threatening strike action due to low wages and poor working conditions. A clinical trial for two treatments and emergency use authorization for a diagnostic test have recently begun. Officials are still working to identify the initial case and trace contacts of infected individuals.

The Ebola outbreak in the Democratic Republic of Congo, declared in mid-May, is the "fastest growing" ever, according to African health authorities. The World Health Organization reported 1,759 confirmed cases and 600 confirmed deaths as of Thursday. Wessam Mankoula of the Africa Centres for Disease Control and Prevention stated the current outbreak has seen more cases in its initial weeks than the deadliest 2013-16 West Africa outbreak. The virus is reportedly spreading faster than response efforts, with cases estimated to double every 28 days. A total of US$1.4 billion is needed for the disease and humanitarian response.

The latest Ebola outbreak in Congo has reached a death toll of 600, with 1,759 confirmed cases. Two new suspected cases have been reported in Kisangani, Tshopo province, an area previously unaffected by the outbreak. One of these cases is linked to the Nia-Nia health zone in Ituri province, where the outbreak began, while the other has no apparent connection to known outbreaks. This outbreak, caused by the rare Bundibugyo virus, was officially declared on May 15th by Congolese authorities. Efforts to control the virus are challenged by funding shortages, attacks on health centers, and ongoing conflict in eastern Congo. Clinical trials for a treatment began last week.