Tomahawks, B-2 stealth bombers and attack drones pound over 1,000 Iranian targets in 24-hour blitz

U.S. forces launched a sweeping military assault on Iranian targets on Saturday, unleashing overwhelming air, sea and missile power in a coordinated operation with Israel. The mission — dubbed "Operation Epic Fury" — began at 1:15 a.m. and struck more than 1,000 sites across Iran within its first 24 hours, according to U.S. Central Command (CENTCOM). Iranian Supreme Leader Ali Khamenei and dozens of senior regime officials were eliminated in the strikes. The barrage featured B-2 stealth bombers, F-22 and F-16 fighter jets, A-10 attack aircraft, EA-18G electronic warfare planes, and an array of airborne early warning and communications platforms, CENTCOM said. SUSTAINED WAR WITH Iran COULD DRAIN US MISSILE STOCKPILES, TEST ESCALATION CONTROL Missile defense systems, including Patriot interceptors and THAAD anti-ballistic missile defenses, were deployed as part of the operation. Other assets included RC-135 reconnaissance aircraft, MQ-9 Reaper drones, HIMARS rocket systems, nuclear-powered aircraft carriers , guided-missile destroyers, refueling tankers, and C-17 and C-130 transport aircraft, CENTCOM said. The command also released images of Tomahawk cruise missiles, as well as F-18 and F-35 fighter jets roaring into combat, according to Reuters. CENTCOM additionally confirmed it deployed one-way attack drones in combat for the first time. DOZENS OF TOP IRANIAN REGIME OFFICIALS, SUPREME LEADER KILLED IN ISRAELI STRIKES The Low-Cost Unmanned Combat Attack System — known as LUCAS — is modeled after Iran’s Shahed drones. "CENTCOM's Task Force Scorpion Strike — for the first time in history — is using one-way attack drones in combat during Operation Epic Fury," CENTCOM wrote on X. "These low-cost drones, modeled after Iran's Shahed drones, are now delivering American-made retribution." Developed by Arizona-based engineering firm SpektreWorks, the LUCAS drone can be launched from catapults, vehicles or mobile ground platforms, according to Business Insider . The drones cost roughly $35,000 each, Reuters reported. KEY MILITARY SITES TARGETED INSIDE Iran AS PART OF COORDINATED US-ISRAELI STRIKES The strikes targeted command and control centers, the Islamic Revolutionary Guard Corps (IRGC) Joint Headquarters and Aerospace Forces Headquarters, integrated air defense systems, ballistic missile sites, Iranian Navy ships and submarines, anti-ship missile sites and military communications infrastructure , according to CENTCOM. Iran retaliated by launching waves of missiles across the Middle East, targeting major U.S. bases in Qatar, Bahrain, Kuwait and the United Arab Emirates, Business Insider reported. Three U.S. service members were killed and five others were "seriously wounded" as part of Operation Epic Fury, CENTCOM said Sunday morning. The joint military operation is expected to carry on for days. CENTCOM did not immediately respond to Fox News Digital's request for comment. Reuters and Fox News Digital's Michael Dorgan contributed to this report.